What is the meaning of Ọ?

The letter o with a dot below.

A letter of the Efik alphabet, written in the Latin script.

The twenty-fifth letter of the Igala alphabet, called ọ́ọ̀ and written in the Latin script.

The twenty-fourth letter of the Isoko alphabet, written in the Latin script.

3rd person singular pronoun (he/she/it)

The twenty-fifth letter of the Igbo alphabet, written in the Latin script.

(personal, epicene) he, she, it

The letter o in thanh nặng tone.

The seventeenth letter of the Yoruba alphabet, called ọ́ and written in the Latin script.

The name of the Latin script letter Ọ/ọ.

you (second-person singular non-honorific object pronoun following a high-tone monosyllabic verb)

you (second-person singular non-honorific object pronoun following a low- or mid-tone monosyllabic verb)

him, her, it (third-person singular non-honorific object pronoun following a monosyllabic verb with a high-tone /ɔ/)

him, her, it (third-person singular non-honorific object pronoun following a monosyllabic verb with a low- or mid-tone /ɔ/)

Source: wiktionary.org