What is the meaning of Irritation?

The act of irritating or annoying

The state of being irritated

A things or person that annoys

a state of inflammation or painful reaction to allergy or cell-lining damage.

A condition of morbid excitability or oversensitiveness of an organ or part of the body; a state in which the application of ordinary stimuli produces pain or excessive or vitiated action.

irritation (all senses)

Source: wiktionary.org