What is the meaning of Appliqué?

Alternative spelling of applique

Alternative spelling of applique

Of a red blood cell infected by the malarial parasite Plasmodium falciparum, assuming a form in which the early trophozoite of Plasmodium falciparum parasitises the marginal portion of the red blood cell, appearing as if the parasite has been “applied”.

past participle of appliquer

diligent, industrious, hardworking, careful

applied

Source: wiktionary.org